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Pain promoter plays unexpected role in central nervous system

Despite all the attention it draws in patients, pain has only in recent years been deemed a subject worthy of scientific scrutiny. “It really was the Cinderella of medicine,” said researcher Clifford...

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Researchers identify genes that trigger depression

A substance known as CREB controls gene expression in the brain. It also appears to be active in mood disorders. A group of Harvard researchers at McLean Hospital in Belmont, Mass., have developed...

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Pain and pleasure activate same brain structures

David Borsook is a Harvard Medical School associate professor of radiology, who both treats patients and conducts research. “Over 15 years of seeing patients with pain it became obvious that we do not...

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A mother’s criticism touches nerve in formerly depressed

Formerly depressed women show patterns of brain activity when they are criticized by their mothers that are distinctly different from the patterns shown by never-depressed controls, according to a new...

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Long-lasting nerve block could change pain management

Harvard researchers at Children’s Hospital Boston have developed a slow-release anesthetic drug-delivery system that could potentially revolutionize treatment of pain during and after surgery, and may...

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Researchers identify the brain’s on-off switch for fear

Harvard researchers at McLean Hospital have identified a particular protein in the brain that serves as a trigger for the body’s innate fear response. This discovery suggests a potential target for...

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